Sickle cell trait (and disease, they are different forms of the same thing) is thought to be a defense against malaria. It can lead to negative health outcomes, but it isn't transmissible (except maybe through blood transfusion, even then the conditions have to be right for red blood cells to sickle) and is thus not a public health issue. It's literally an example of evolution and is very cool, actually.
"Mersa", I assume you mean MRSA, is a hospital-borne staph infection resistant to one particular type of medicine.
STDs (including HIV, tho it is not exclusively transmitted through sexual contact) really don't care about races, gender identities, nor any other demographic. They are equal opportunity infections.