While European technology, education, trade, history, and philosophy certainly could have been a boon to the indigenous people of the Americas, in practice it is a very mixed bag. Centuries of oppression, marginalization, exploitation, and genocide are part of Columbus' legacy. The same Columbus who was stripped of governorship for being corrupt and cruel, even for the time.
Christianity alone, the only thing the OP credits Columbus with beinging, not really worth the bad things that came after as well. As for the negatives on the indigenous people's side... just cause it's a different religion doesn't make it witchcraft. The human sacrifice, at least by the Aztecs and and anything similar? I'm cool with that being stopped. The method it was stopped was completely fucked, however, and the scale might have been exaggerated by the Spanish. But yeah, when a focal point of the religion is the ritual slaughter of. Lot of people, and you effectively enslave your neighbors for sacrifice gathering wars? Certainly don't need that to continue.
So that's one partial point from the entire list, his grade for the situation is an F.